What Is Hybrid HA Injectable (Structura)?

Structura is a hyaluronic acid injectable formulated with 90mg/2ml and developed using IBSA’s NAHYCO® hybrid technology. It is intended for use in the superficial fat layer just beneath the skin.

This targeted approach aims to address age-related facial changes by supporting collagen, elastin, and fat cell activity within these areas. Structura is designed to maintain facial support and skin structure over time.

While the original focuses on hydration and elasticity in the dermis, Structura is intended for a deeper layer. It may be considered by individuals who have midface volume loss, early skin laxity, or changes along the jawline.

Key Benefits of Structura

Structura offers a bio-remodelling approach to facial rejuvenation that works beneath the skin’s surface—targeting the subcutaneous fat layer to support volume and contour restoration. This injectable treatment performs a lipolifting effect, acting within the fat compartments to restore structural support without changing the natural shape or expression of the face.

Deep Tissue Bio-Remodelling

Structura is injected into specific fat compartments under the skin. This allows for a lipolifting action, helping restore volume and contour by supporting tissue renewal and repositioning.

Stimulates Natural Collagen, Elastin & Fat Cells

Rather than simply adding volume, it promotes the activity of collagen, elastin, and adipocytes (fat cells), supporting long-term skin structure and resilience.

Hydrates and Firms Without Bulk

Patients can expect firmer, more elastic skin over treated areas, while maintaining natural facial expressions—no exaggerated fullness.

Biological "Scaffold" Effect

The gel acts as a supportive matrix within the fat layer, helping to reposition and lift sagging areas such as the cheeks and jawline.

Minimally Invasive, Cannula-Based Delivery

Using a blunt cannula, treatment typically requires just two entry points—reducing the risk of bruising and allowing for a quicker recovery.

High Safety Profile

Structura is thermally stabilised and contains no chemical cross-linkers, which reduces the potential for certain side effects sometimes associated with conventional fillers.

Target Areas and Specific Concerns

Skin Concerns Addressed

Structura is designed for individuals experiencing age-related structural changes in the face. It targets areas affected by fat loss and skin-thinning factors, often responsible for facial sagging and loss of definition. This treatment may be suitable for those looking to address:

  • Volume loss due to ageing
  • Thinning or weakened structural support beneath the skin
  • Midface sagging and skin laxity.
  • Flattened cheekbones or early jowl heaviness
  • Mild facial asymmetry from fat pad descent

Areas Commonly Treated

Structura focuses on the mid to lower face, where facial volume tends to diminish over time. Common treatment areas include:

  • Cheeks (malar region)
  • Jawline
  • Temples
  • Chin and lower face
  • Deep nasolabial folds

Who It’s Best Suited For

Structura may be suitable for patients looking to support facial contours without relying on traditional fillers. Candidate profiles include:

Who It’s Best Suited For

Structura may be suitable for patients looking to support facial contours without relying on traditional fillers. Candidate profiles include:

structura key patient features

Sinkers

Individuals with slimmer, more angular features may experience hollow cheeks, sunken under-eyes, or general facial volume reduction. Structura is designed to act within the superficial fat layer, where it may help support areas affected by volume loss and contribute to a softer appearance.

Saggers

Those with fuller faces who are noticing early changes in midface definition or mild heaviness around the jawline may consider Structura. It is intended to support facial tissues in areas where volume descent may be contributing to visible changes.

It may also be appropriate for:

  • Adults aged 35 and above showing early signs of facial ageing
  • Patients looking for a gentle, natural lift without volume-heavy fillers
  • Individuals experiencing facial flatness after weight loss or medication-related fat loss.

Treatment Overview at Lux Medical Clinic

At Lux Medical Clinic, every Structura treatment is customised to suit your facial structure and ageing concerns. From assessment to aftercare, we ensure a patient-centred approach that prioritises both safety and subtle, natural-looking outcomes.

Female patient receiving Profhilo Structura treatment

Consultation

Your treatment begins with a detailed medical consultation. During this session:

  • Our doctor will carry out a comprehensive facial assessment to evaluate volume distribution and structural changes.
  • Based on your facial structure, you may fall into a ‘Sinker’ or ‘Sagger’ profile. This helps guide injection site selection and overall treatment planning.
  • In some cases, Structura may be used alongside the original to support both skin quality and deeper tissue structure.

This approach aims to align your treatment with your individual goals while supporting a natural-looking result.

Procedure

The Structura treatment is performed in-clinic and typically takes around 15 to 20 minutes. The steps include:

  • Cleansing and numbing of the skin at the planned entry points
  • A single cannula entry point per side, usually positioned near the ear
  • The retrograde linear threading technique is used to deliver the product into the superficial fat layer
  • The hyaluronic acid gel is gently fanned through the adipose tissue compartments for smooth, even integration
  • A light massage may be done to guide product distribution, if needed

Unlike the original, which is injected into fixed dermal Bio Aesthetic Points (BAP) to support skin hydration, Structura is placed deeper, within the fat layer, using a cannula. This technique may reduce the number of injection points and is designed to minimise discomfort, while supporting the intended structural treatment approach.

Results and Post-Care

Expected Results

Some patients may observe changes within 2 to 4 weeks, as the bioremodelling process takes place.

Visible changes, such as enhanced midface structure and improved skin appearance, may become more noticeable around 4 weeks after the second session.

The duration of results can vary based on factors such as individual response, lifestyle, and the ageing process.

Aftercare Tips

To support recovery and ensure the best outcome:

  • Avoid pressing or massaging the treated areas for the first 24 hours
  • Refrain from strenuous physical activity, saunas, or facials for 48 hours
  • Skincare and makeup can usually be resumed the following day, unless advised otherwise

While downtime is minimal, some mild swelling or redness at the entry points may occur and typically resolves within a few hours to a day.

Frequently Asked Questions (FAQs)

Is Structura the same as Injectable Skinbooster?

No. While both use NAHYCO® hybrid hyaluronic acid, Structura is injected into the fat layer to support volume and facial structure. In contrast, the original is injected into the skin to support hydration and elasticity.

Can Structura replace fillers?

Not exactly. Structura is designed to support collagen and fat tissue activity, which may help enhance facial definition without adding volume like traditional fillers.

How long do results last?

Results may vary between individuals, but effects are often maintained for several months. A booster session at 4 months may be recommended to prolong treatment effects.

What age is suitable for Structura?

This treatment is generally considered for adults aged 35 and above who are showing early signs of midface volume reduction or skin laxity.

Is it safe for sensitive skin?

Yes. Structura contains hyaluronic acid and does not include chemical cross-linkers. It is generally suitable for various skin types, including sensitive skin, but individual responses may vary.

Can Structura be combined with 64mg HA Injectable Skinbooster?

Yes. In many cases, it can be used to support skin hydration and texture, while Structura targets areas beneath the skin to support facial structure. Your doctor will advise whether this combination suits your treatment goals.

Price of Structura

At Lux Medical Clinic, each Structura session is tailored to your facial structure and treatment goals. The procedure is performed by a certified doctor using a cannula technique designed to support targeted product placement and reduce the number of injection points.

Each session includes:

  • 2 ml of Structura
  • Personalised treatment plan based on your facial profile
  • Cannula-based delivery for safety and comfort

Treatment Fee:
From SGD 1100*
A personalised quote will be provided during consultation.

Note: Pricing may vary depending on individual needs and whether combination therapy is recommended.

What Makes Structura Different from Injectable Skincare?

Feature Injectable Skincare Structura

Target Layer

Dermis / superficial

Subcutaneous fat (adipose)

Purpose

Hydration, skin appearance

Structure, lift, firmness

HA Concentration

64mg / 2ml

90mg / 2ml

Injection Method

Needle, 5 BAP points

Cannula, 1 entry point per side

Spread

Wide skin diffusion

Localised Structural integration

Ideal For

Fine lines, dull or crepey-looking skin

Sagging, volume loss, and facial hollowing

While Injectable Skincare supports skin hydration and surface texture, Structura is designed to act in deeper layers to support the underlying facial structure. Used together, they offer a layered approach to treatment. This supports both the skin and deeper facial layers in a coordinated plan based on your treatment goals.

Before and After

Due to regulatory guidelines in Singapore, we do not display before-and-after images on our website.

However, during your consultation, our doctor can discuss expected outcomes and walk you through what to anticipate based on your unique facial anatomy and treatment goals.

Why Choose Lux Medical Aesthetic Clinic?

At Lux Medical Clinic, we believe aesthetic treatments should enhance—not alter—your natural features. Every Structura procedure is carefully planned by a certified aesthetic doctor, with a focus on treatment techniques tailored to individual needs. Our clinic uses approved hyaluronic acid injectables and protocols aligned with current clinical practice to support treatment safety and patient comfort.

We take the time to understand your concerns and will only recommend treatments suited to your skin structure, lifestyle, and preferences.

Taking the Next Step

If you’re starting to notice sagging, volume loss, or midface changes—but prefer a natural look without dermal fillers—Structura may be an appropriate option.

Book a personalised consultation at Lux Medical Clinic to explore whether this treatment is suitable for your needs. We’ll guide you through the process, answer your questions, and recommend a plan that aligns with your aesthetic goals.

Book an Appointment

Important Information

*prices stated are exclusive of 9% GST.

Nothing in this website constitutes or is intended to constitute medical advice and readers rely on the statements contained herein at their own risk. Treatment results, experiences and downtime (if any) may vary by individuals. Please make an appointment with our clinic for a thorough medical assessment of your condition and treatment requirements.

Dr. Kellyn Shiau

Dr Kellyn Shiau graduated from University with a Bachelor of Medicine and Surgery. She also holds a Graduate Diploma in Family Medicine from the National University of Singapore.

After graduation, she practiced medicine in various major restructured hospitals and also privately with a well-established medical group in Singapore. She is experienced and has trained extensively in medical aesthetics for many years.

Dr. Kellyn Shiau