If you’re noticing a gradual loss of skin firmness, changes in texture, or the appearance of fine lines and post-acne marks, Heterologous Type I Collagen (HTIC) offers a non-filler injectable option that works with your skin’s natural repair processes.
Heterologous Type I Collagen (HTIC) is a bio-remodelling skin rejuvenation treatment, a collagen biostimulator. It contains sterile, purified Heterologous Type I Collagen (HTIC) derived from equine sources. Unlike dermal fillers that are used to restore facial volume, HTIC is intended to support the skin’s natural collagen production process, functioning as a collagen biostimulator.
This treatment is typically applied to areas such as the face, neck, décolletage, and hands. It may also be considered for skin that shows signs of ageing, acne scarring, or stretch marks. The formulation is biocompatible and used in aesthetic medicine to address changes in skin texture, elasticity, and firmness by working with the skin’s existing regenerative functions.
HTIC works once injected into the skin. The collagen powder is hydrolysed—broken down into amino acids and peptides that interact with the skin’s natural repair processes. As these compounds are structurally similar to human collagen, they may help activate fibroblasts—cells in the skin involved in collagen synthesis and supportive of the skin’s structure, elasticity, and firmness. This process supports the gradual production of endogenous Type I and III collagen.
In addition, it may encourage the proliferation of fibroblasts, contributing to the synthesis of collagen fibres that support skin quality. Beyond this, the injected collagen helps form a structural framework (or scaffold) that supports the reorganisation of the extracellular matrix.
Type 1 collagen injections is not intended to add volume or change facial contours. Instead, it supports the skin’s natural renewal pathways over a series of sessions.
Heterologous Type I Collagen (HTIC) injections are considered by individuals who prefer a regenerative approach to skin support, without the volumising effect associated with traditional dermal fillers. This treatment is used in clinical settings to support the skin’s natural renewal processes.
HTIC engages fibroblasts involved in the skin’s natural production of Type I and III collagen, which are essential for maintaining skin structure.
It is used in aesthetic practice to manage roughness, dullness, and other surface-level skin changes.
When applied to areas such as the face, eyes, neck, décolletage, and hands, this treatment may help maintain skin firmness and elasticity over time.
HTIC is used in aesthetic practice as part of a bio-remodelling approach. It acts as a scaffold within the dermis, supporting the skin’s structural matrix and collagen activity. This may assist the skin’s natural regeneration processes over time.
May be considered as part of a treatment plan for post-acne marks, stretch marks, or other mild skin irregularities, as assessed by your doctor.
HTIC is used to support the skin’s structural quality and appearance over time. It works with the skin’s natural renewal functions, without changing facial contours or adding volume.
HTIC is formulated with purified Type I collagen derived from equine sources. It is used in aesthetic practice as a non-surgical injectable and is generally associated with a short recovery time. The formulation is free of synthetic chemicals or preservatives and supports the skin’s structural matrix as part of non-invasive treatment plans.
Any visible changes tend to appear progressively with repeated sessions, depending on the individual’s skin condition and treatment plan.
Your doctor will assess whether this treatment is suitable for your skin concerns during a detailed consultation.
Heterologous Type I Collagen Injection is used in clinical aesthetic practice to support the skin’s natural collagen process. It is commonly applied in areas where signs of ageing or surface-level texture changes may be present.
| Aspect | Details |
|---|---|
Recommended Sessions |
4 sessions |
Recommended Interval |
Every 2 weeks |
Duration per Session |
30 minutes |
Downtime |
Minimal, 1-3 days. small blebs after injection |
Price |
Starting from $ 1,000* |
Maintenance phase |
Once every 2 to 6 months, or as advised |
Before starting treatment, a detailed consultation will be scheduled to evaluate your skin condition, understand your concerns, and determine if HTIC is an appropriate option for your needs.
Each session typically takes around 20 to 30 minutes. The steps may include:
Mild sensations such as light pressure or stinging may occur during treatment. Your doctor will guide you through the process and address any concerns to ensure your comfort throughout the session.
HTIC is typically administered as a series of treatments spaced over several weeks. The exact schedule may vary depending on your skin condition and treatment goals.
While every skin journey is different, some people may notice early improvements after 1 to 2 sessions. For most, visible changes take shape more gradually across 4 to 8 weeks as the skin responds to the full course of treatment.
Your doctor will tailor the treatment schedule and maintenance plan according to your skin’s response and desired outcomes.
HTIC is generally regarded as a low-downtime procedure. Most people are able to return to daily activities shortly after treatment. However, mild and temporary effects may occur, such as:
These effects typically resolve within 1 to 3 days. Your doctor will provide aftercare instructions to help support a smooth recovery.
To support your skin’s recovery after HTIC, it’s recommended to follow these care tips:
HTIC is priced based on the number of syringes used and the total number of sessions required. The standard recommendation is 4 sessions using one 5ml syringe per session.
Cost:
S$1,000* per session
Your doctor will provide a personalised treatment plan and cost estimate during your consultation.
Due to Ministry of Health (MOH) regulations, we cannot publicly display actual before-and-after photos. These regulations are in place to ensure the privacy and confidentiality of patients while maintaining ethical standards in advertising medical treatments.
During your consultation, and where relevant, your doctor may share internal clinical images for reference. These images are shown only with prior patient consent and are used solely for educational purposes during clinical discussion.
Heterologous Type I Collagen (HTIC) is derived from purified equine collagen and processed to reduce immunogenicity. It is used under medical supervision and may be suitable for various skin types, including delicate areas such as the under-eye. Its formulation incorporates patented processing methods and is used in aesthetic practice for its collagen-supporting properties.
As a collagen stimulator, HTIC is used to support the skin’s natural renewal processes. It is administered through non-thermal, non-volumising means and works alongside the body’s cellular activity. This approach is intended to assist in maintaining skin structure and texture over time.
At Lux Medical Clinic, every treatment begins with a thorough consultation. We focus on understanding your skin’s needs and presenting realistic care options. Here’s what to expect:
We prioritise a respectful, medically sound environment where you feel supported and informed throughout your treatment journey.
HTIC may be considered for individuals seeking a collagen-supporting injectable that does not add volume or require extended downtime.
If you’re exploring whether this treatment is suitable for your skin concerns, our doctor will guide you through the available options during a detailed consultation. Clinical assessment is an important step to ensure the treatment aligns with your skin type and overall care goals.
Important Information
*prices stated are exclusive of 9% GST.
Nothing in this website constitutes or is intended to constitute medical advice and readers rely on the statements contained herein at their own risk. Treatment results, experiences and downtime (if any) may vary by individuals. Please make an appointment with our clinic for a thorough medical assessment of your condition and treatment requirements.
Dr Kellyn Shiau graduated from University with a Bachelor of Medicine and Surgery. She also holds a Graduate Diploma in Family Medicine from the National University of Singapore.
After graduation, she practiced medicine in various major restructured hospitals and also privately with a well-established medical group in Singapore. She is experienced and has trained extensively in medical aesthetics for many years.
